46221 ZIP Code, Indianapolis, IN

46221 is a ZIP code in Indianapolis, Indiana in Marion County. It covers 20 square miles of land. The closest ZIP codes are 46217, 46241 and 46183. 27,027 people live here in 10,117 households. At about 1,353 people per square mile it has suburban density, and owners and renters are mixed (62% own). Median household income is $65,280, close to the Indiana median of $71,957.

Quick facts

Key figures

MeasureValue
Residents27,027
Households10,117
Median household income$65,280
Income per person$29,663
Median age34.5
Homeowners61.8%
Median home value$191,300
Median rent$1,137
Bachelor's degree or higher16.0%
Average commute (minutes)27.1
Households with kids under 1830.1%
Moved in the past year12.3%
Below the poverty line18.4%
Broadband internet92.6%
Speak a non-English language at home13.8%

Household income

% of householdsValue
<$10K5.2%
$10–15K3.1%
$15–25K5.9%
$25–35K9.8%
$35–50K16.5%
$50–75K17.4%
$75–100K15.9%
$100–150K15.3%
$150–200K8.5%
$200K+2.4%

Age

% of all residentsValue
<1014.1%
10–1913.9%
20–248.5%
25–3414.7%
35–4412.0%
45–5412.8%
55–6412.7%
65–748.0%
75+3.5%

Tenure

% of housing unitsValue
Owned, with mortgage40.3%
Owned outright16.0%
Rented34.6%
Vacant9.2%

Type of building

% of housing unitsValue
Detached house75.6%
Townhome4.4%
2–4 units3.8%
5–19 units12.6%
20+ units1.8%
Mobile / other1.7%

Businesses in 46221

341 business establishments with 10,775 employees (ZIP Codes Business Patterns 2023).

EDDM carrier routes

46221 has 15 USPS carrier routes with 10,806 residential and 364 business mailboxes. Open the EDDM route map.

Carrier routes in 46221

46221 has 15 USPS carrier routes (8 city (C), 7 rural (R)) with 10,806 residential and 364 business mailboxes. Routes range from 339 homes (C027) to 1,094 homes (C020); the median route has 699 homes. The Census counted 10,117 households in 46221 (2020–2024 average); USPS counts current mailboxes, including new and vacant homes.

Homes per routeRoutes
1–2490
250–4992
500–7497
750–9995
1,000–1,4991
1,500+0

Best routes in 46221 for…

Most businesses

For B2B offers: office supplies, cleaning, IT, catering and commercial services.

  1. Route C015 — USPS business mailboxes 82, 345 homes
  2. Route C024 — USPS business mailboxes 62, 908 homes
  3. Route C003 — USPS business mailboxes 40, 509 homes
  4. Route R043 — USPS business mailboxes 35, 619 homes
  5. Route C004 — USPS business mailboxes 34, 692 homes

Select these 5 routes on the route map

Every carrier route in 46221

RouteTypeHomesBusinessesEst. median incomeEst. ownersEst. families with kidsEst. moved in past year
C003City50940$28,971———
C004City69234$67,970———
C009City71824$28,971———
C015City34582$64,170———
C020City1,0947$51,020———
C023City89330$51,385———
C024City90862$80,766———
C027City3393$53,948———
R026Rural8601$77,496———
R034Rural8240$93,399———
R043Rural61935$59,613———
R046Rural66833$77,496———
R047Rural6996$99,591———
R050Rural6742$105,013———
R080Rural9645$99,591———

Income, owners, families and movers are estimates for each route (how we estimate them); mailbox counts are current USPS figures. Open 46221 on the EDDM route map.

How route demographics are estimated

Mailbox counts come from USPS; demographics are estimates

The number of homes and businesses on each carrier route is the current USPS EDDM count. The Census Bureau does not publish figures for carrier routes, so income, homeownership, ages, families, movers and housing age on a route are EDDM2GO estimates built from Census block groups (neighborhood areas of roughly 600 to 3,000 people).

How a route gets its figures: the block-group length-share method

We trace each route's streets every 25 meters and record which block group each stretch falls in. The route's homes are spread along its streets in proportion to length, so a route with 60% of its street length in one block group is assumed to have 60% of its homes there. Each block group then contributes its Census counts in proportion to the share of its housing units that sit on the route (capped at the whole block group). Medians are recalculated from the combined income, home-value and age brackets, the way the Census Bureau computes them, not averaged.

Margins of error

Census survey figures carry a margin of error at 90% confidence; we carry it through the calculation and show it as ±. Our margins treat the route-to-block-group split as exact, so the real uncertainty is larger. Routes with fewer than 100 estimated households, large margins, or streets we could not place are flagged.

Different years

USPS mailbox counts are current. Census figures are 5-year averages for 2020–2024, so a new subdivision may have more homes on the route today than the Census counted. Use the route figures to compare routes with each other, not as an exact head count.

Why some routes show identical figures

Two routes that run through the same block group get the same percentages and medians, because the Census publishes one set of figures for the whole block group. Their mailbox counts still differ, and those are exact.

Route and mailbox counts: USPS EDDM route data. Route demographics: EDDM2GO estimates from U.S. Census Bureau American Community Survey 5-year block-group data (2020–2024) and 2024 cartographic block-group boundaries. This product uses the Census Bureau Data API but is not endorsed or certified by the Census Bureau.

Nearby ZIP codes

Areas that include 46221

Mail every home in 46221

Route counts on this page price as Full Service 6.5 × 9 postcards: we print, bundle by carrier route and hand the mailing to USPS. Prefer to take it to the Post Office yourself? Print only costs less and you pay postage at drop-off.

Indianapolis EDDM mailing

EDDM guides

ZIP code statistics describe the Census ZIP Code Tabulation Area (ZCTA) 46221, which approximates the USPS ZIP code area. Census figures: American Community Survey 5-year estimates, 2020–2024.

Frequently asked questions

What city is 46221 in?
46221 is a Indianapolis, IN mailing address. By land area, 100% lies inside Indianapolis city (balance).
What county is 46221 in?
46221 is in Marion County.
What is the population of 46221?
About 27,027 people (±1,544), according to the Census Bureau's American Community Survey 5-year estimates for 2020–2024. The 2020 Census counted 27,991.
What is the median household income in 46221?
$65,280 (±$8,302), compared with $71,957 for Indiana as a whole. Half the households in the ZIP code earn more and half earn less.
How many carrier routes and mailboxes are in 46221?
15 USPS carrier routes with 10,806 residential and 364 business mailboxes (11,171 in all), from the route data stored by EDDM2GO. An EDDM mailing can target any combination of these routes.
What ZIP codes are near 46221?
The closest, measured center to center: 46217 (2.9 mi, Indianapolis city (balance), IN), 46241 (3.2 mi, Indianapolis city (balance), IN), 46183 (3.7 mi, Indianapolis city (balance), IN), 46225 (5 mi, Indianapolis city (balance), IN), 46231 (5.2 mi, Indianapolis city (balance), IN) and 46113 (5.3 mi, Indianapolis city (balance), IN).

This product uses the Census Bureau Data API but is not endorsed or certified by the Census Bureau.